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PRMT6 Monoclonal Antibody
PRMT6 Monoclonal Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: N0738
Reactivity:Human,Mouse,Rat
Applications:WB,IHC-p,IF/ICC
Modification:Unmodfied/ Total
Source:Monoclonal Mouse
Storage and Stability:-20°C/1 year

$210
Product Details
Product Name
PRMT6 Monoclonal Antibody
Description
The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity. [provided by RefSeq, Sep 2011],
Catalog No
N0738
Reactivity
Human,Mouse,Rat
Applications
WB,IHC-p,IF/ICC
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
Western Blot: 1/1000 - 1/2000. Immunohistochemistry: 1/500 - 1/1000. Immunofluorescence: 1/100 - 1/500. Not yet tested in other applications.
Purification
Affinity purification
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
PRMT6; HRMT1L6; Protein arginine N-methyltransferase 6; Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6; Histone-arginine N-methyltransferase PRMT6
Molecular Weight (Da)
Gene Name
PRMT6
Protein Name
Protein arginine N-methyltransferase 6
Human Gene ID
55170
Human Swiss Prot No.
Q96LA8
Immunogen
Purified recombinant human PRMT6 protein fragments expressed in E.coli.
Specificity
PRMT6 Monoclonal Antibody detects endogenous levels of PRMT6 protein.
Formulation
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.
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