This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Catalog No
A1074
Reactivity
Human, Rat, Mouse
Applications
WB, ELISA
Modification
Phospho Specific
Source
Polyclonal Rabbit
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using IRAK1 (Phospho-Thr209) Antibody
Author:
Zhen Ning Wee, Siti Maryam J. M. Yatim, Vera K Kohlbauer, Min Feng, Jian Yuan Goh, Yi Bao, Puay Leng Lee, Songjing Zhang, Pan Pan Wang, Elgene Lim, Wai Leong Tam, Yu Cai, Henrik J Ditzel, Dave S. B. Hoon, Ern Yu Tan & Qiang Yu