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Primary Antibodies
UHRF1(N-term) mouse mAb
UHRF1(N-term) mouse mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: N0767
Reactivity:Human,Mouse
Applications:WB
Modification:Unmodfied/ Total
Source:Monoclonal Mouse
Storage and Stability:-20°C/1 year

$160
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Synthesis and Degradation
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UHRF1(N-term) mouse mAb

Western blot detection of UHRF1 in Mouse heart.293T.HelaNE and Hela cell lysates using UHRF1 mouse mAb (1:1000 diluted).Predicted band size: 90KDa.Observed band size: 90KDa.

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Product Details
Product Name
UHRF1(N-term) mouse mAb
Description
ubiquitin like with PHD and ring finger domains 1(UHRF1)Homo sapiens. This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. It is regarded as a hub protein for the integration of epigenetic information. This gene is up-regulated in various cancers, and it is therefore considered to be a therapeutic target. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene exists on chromosome 12. [provided by RefSeq, Feb 2014],
Catalog No
N0767
Reactivity
Human,Mouse
Applications
WB
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
wb 1:1000
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
Ac2-121;AL022808;E3 ubiquitin-protein ligase UHRF1;EC 6.3.2.-;FLJ21925;Hnp95 Huhrf1; HuNp95;ICBP90;Inverted CCAAT box binding protein of 90 kDa;Inverted CCAAT box binding protein, 90-Kd;Inverted CCAAT box-binding protein of 90 kDa;Liver regeneration-related protein LRRG126;MGC138707;NP95;Nuclear phosphoprotein, 95-KD;Nuclear protein 95;Nuclear zinc finger protein Np95;RING finger protein 106;RNF106;Transcription factor ICBP90; Ubiquitin like containing PHD and RING finger domains protein 1;Ubiquitin like PHD and RING finger domain containing protein 1;Ubiquitin-like PHD and RING finger domain-containing protein 1;Ubiquitin-like protein containing PHD and RING finger domains 1; Ubiquitin-like with PHD and ring finger domains 1;Ubiquitin-like, containing PHD and RING finger domains, 1;Ubiquitin-like-containing PHD and RING finger domains protein 1;UHRF1;UHRF1_HUMAN.
Molecular Weight (Da)
Gene Name
uhrf1
Protein Name
Human Gene ID
29128
Human Swiss Prot No.
Q96T88
Immunogen
Purified recombinant human UHRF1 protein fragments expressed in E.coil.
Specificity
This antibody detects endogenous levels of UHRF1 and does not cross-react with related proteins
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Primary Antibodies

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    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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