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Patched Antibody

Catalog No : C0296
  • Reactivity
  • Applications
    WB,IHC-p,IF(paraffin section),ELISA
  • Modification
  • Source
    Polyclonal Rabbit
  • Storage and Stability
    -20°C/1 year
  • Size
    50 μl
  • Price/Quantity
  • Quantity
  • Product Name
    Patched Antibody
  • Description
    This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently. [provided by RefSeq, Jul 2008]
  • Catalog No
  • Reactivity
    Human, Mouse
  • Applications
    WB, IHC-p, IF(paraffin section), ELISA
  • Modification
  • Source
    Polyclonal Rabbit
  • Dilution
    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
  • Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration
    1 mg/ml
  • Storage and Stability
    -20°C/1 year
  • Other Name
    PTCH1; PTCH; Protein patched homolog 1; PTC; PTC1
  • Molecular Weight (Da)
  • Gene Name
  • Protein Name
    Protein patched homolog 1
  • Human Gene ID
  • Human Swiss Prot No.
  • Immunogen
    The antiserum was produced against synthesized peptide derived from human Patched. AA range:1-50
  • Specificity
    Patched Polyclonal Antibody detects endogenous levels of Patched protein.
  • Formulation
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.