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BMP-4 Antibody
BMP-4 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C40089
Reactivity:Human,Rat,Mouse
Applications:WB,ELISA
Modification:Unmodified/Total
Source:Polyclonal,Rabbit,IgG
Storage and Stability:Store at -20°C/1 year

$150
Product Details
Product Name
BMP-4 Antibody
Description
disease:Defects in BMP4 are the cause of microphthalmia syndromic type 6 (MCOPS6) [MIM:607932]; also known as microphthalmia and pituitary anomalies or microphthalmia with brain and digit developmental anomalies. Microphthalmia is a clinically heterogeneous disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues (anophthalmia). In many cases, microphthalmia/anophthalmia occurs in association with syndromes that include non-ocular abnormalities. MCOPS6 is characterized by microphthalmia/anophthalmia associated with facial, genital, skeletal, neurologic and endocrine anomalies.,function:Induces cartilage and bone formation. Also act in mesoderm induction, tooth development, limb formation and fracture repair.,online information:Bone morphogenetic protein 4 entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer; disulfide-linked (By similarity). Interacts with GREM2 (By similarity) and SOSTDC1. Part of a complex consisting of TWSG1 and CHRD.,tissue specificity:Expressed in the lung and lower levels seen in the kidney. Present also in normal and neoplastic prostate tissues, and prostate cancer cell lines.,
Catalog No
C40089
Reactivity
Human, Rat, Mouse
Source
Polyclonal, Rabbit,IgG
Modification
Unmodified/Total
Applications
WB, ELISA
Dilution
WB 1:1000-2000 ELISA 1:5000-20000
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
Bone morphogenetic protein 4 (BMP-4; Bone morphogenetic protein 2B; BMP-2B)
Molecular Weight (Da or kDa)
45kD
Gene Name
BMP4 BMP2B DVR4
Protein Name
BMP-4
Human Gene ID
652
Human Swiss Prot No.
P12644
Immunogen
Synthesized peptide derived from human BMP-4 AA range: 261-310
Specificity
This antibody detects endogenous levels of Human BMP-4
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (1)