PP2B-Aα Antibody (C40127) | Assay Biotech Inc.

PP2B-Aα Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C40127

Reactivity:Human,Mouse,Rat

Applications:WB,IHC

Modification:Unmodified/Total

Source:Polyclonal,Rabbit,IgG

Storage and Stability:Store at -20°C/1 year

Size:

Price/Quantity $150

Quantity:

Datasheet

SDS

Kinases and Phosphatases

PP2B-Aα Antibody

Immunohistochemical analysis of paraffin-embedded human Breast cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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Product Details

Product Name

PP2B-Aα Antibody

Description

catalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,cofactor:Binds 1 Fe(3+) ion per subunit.,cofactor:Binds 1 zinc ion per subunit.,function:Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates HSPB1 and SSH1.,online information:Calcineurin entry,similarity:Belongs to the PPP phosphatase family.,similarity:Belongs to the PPP phosphatase family. PP-2B subfamily.,subcellular location:Colocalizes with ACTN1 and MYOZ2 at the Z line in heart and skeletal muscle.,subunit:Composed of two components (A and B), the A component is the catalytic subunit and the B component confers calcium sensitivity. Interacts with TORC2/CRTC2, MYOZ1, MYOZ2 and MYOZ3.,

Catalog No

C40127

Reactivity

Human, Mouse, Rat

Source

Polyclonal, Rabbit,IgG

Modification

Unmodified/Total

Applications

WB, IHC

Dilution

WB 1:500-2000;IHC 1:50-300

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Storage and Stability

Store at -20°C/1 year

Other Name

Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform (EC 3.1.3.16; CAM-PRP catalytic subunit; Calmodulin-dependent calcineurin A subunit alpha isoform)

Molecular Weight (Da or kDa)

57kD

Gene Name

PPP3CA CALNA CNA

Protein Name

PP2B-Aα

Human Gene ID

5530

Human Swiss Prot No.

Q08209

Immunogen

Synthesized peptide derived from human PP2B-Aα