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Primary Antibodies
NUMB Antibody
NUMB Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C40196
Reactivity:Human,Mouse,Rat
Applications:WB,ELISA
Modification:Unmodified/Total
Source:Polyclonal Rabbit
Storage and Stability:-20°C/1 year

$205
# Datasheet #
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Neurobiology
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NUMB Antibody

Western Blot analysis of A549 cells using NUMB Polyclonal Antibody. Secondary antibody(catalogNo.:SA0002) was diluted at 1:20000

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Product Details
Product Name
NUMB Antibody
Description
The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Catalog No
C40196
Reactivity
Human, Mouse, Rat
Applications
WB, ELISA
Modification
Unmodified/Total
Source
Polyclonal Rabbit
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
NUMB; Protein numb homolog; h-Numb; Protein S171
Molecular Weight (Da)
70804
Gene Name
NUMB
Protein Name
Protein numb homolog
Human Gene ID
8650
Human Swiss Prot No.
P49757
Immunogen
Synthesized peptide derived from the Internal region of human NUMB.
Specificity
NUMB Polyclonal Antibody detects endogenous levels of NUMB protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (2)
Chemotherapy-elicited exosomal miR-378a-3p and miR-378d promote breast cancer stemness and chemoresistance via the activation of EZH2/STAT3 signaling

Author: Yang, Qianxi, Zhao, Shaorong, Shi, Zhendong, Cao, Lixia, Liu, Jingjing, Pan, Teng, Zhou, Dongdong, Zhang, Jin

Date of Publication : 2021-04-06

Hepatic stem cell Numb gene is a potential target of Huang Qi Decoction against cholestatic liver fibrosis

Author: Xu, Wen, Xu, Yan-nan, Zhang, Xu, Xu, Ying, Jian, Xun, Chen, Jia-mei, Chen, Gao-feng, Zhang, Hua, Liu, Ping, Mu, Yong-ping

Date of Publication : 2020-10-15

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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