DHB1 Antibody (C43433) | Assay Biotech Inc.

DHB1 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C43433

Reactivity:Human,Rat,Mouse

Applications:WB,ELISA

Modification:Unmodified/Total

Source:Polyclonal Rabbit

Storage and Stability:-20°C/1 year

Size:

Price/Quantity $205

Quantity:

Datasheet

SDS

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DHB1 Antibody

Western blot analysis of lysates from KB cells, primary antibody was diluted at 1:1000, 4°over night

Delivery

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

Telephone

408-747-0185

Fax

408-747-0145

order@assaybiotech.com

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Product Details

Product Name

DHB1 Antibody

Description

hydroxysteroid 17-beta dehydrogenase 1(HSD17B1) Homo sapiens This gene encodes a member of the 17beta-hydroxysteroid dehydrogenase family of short-chain dehydrogenases/reductases. It has a dual function in estrogen activation and androgen inactivation and plays a major role in establishing the estrogen E2 concentration gradient between serum and peripheral tissues. The encoded protein catalyzes the last step in estrogen activation, using NADPH to convert estrogens E1 and E2 and androgens like 4-androstenedione, to testosterone. It has an N-terminal short-chain dehydrogenase domain with a cofactor binding site, and a narrow, hydrophobic C-terminal domain with a steroid substrate binding site. This gene is expressed primarily in the Placenta and ovarian granulosa cells, and to a lesser extent, in the endometrium, adipose tissue, and prostate. Polymorphisms in this gene have been linked to breast and prostate cancer. A pseudogene of this gene has

Catalog No

C43433

Reactivity

Human, Rat, Mouse

Applications

WB, ELISA

Modification

Unmodified/Total

Source

Polyclonal Rabbit

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Storage and Stability

-20°C/1 year

Other Name

Molecular Weight (Da)

Gene Name

HSD17B1 E17KSR EDH17B1 EDH17B2 EDHB17

Protein Name

Estradiol 17-beta-dehydrogenase 1 (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase type 1) (17-beta-HSD 1) (20 alpha-hydroxysteroid dehydrogenase) (20-alpha-HSD) (E2DH) (Placental 17-beta-hydroxysteroid dehydrogenase)

Human Gene ID

3292

Human Swiss Prot No.

P14061

Immunogen

Synthesized peptide derived from part region of human protein

Specificity

DHB1 Polyclonal Antibody detects endogenous levels of protein.

Formulation

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.