DHI2 Antibody (C43438) | Assay Biotech Inc.

DHI2 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C43438

Reactivity:Human,Rat,Mouse

Applications:WB,ELISA

Modification:Unmodified/Total

Source:Polyclonal Rabbit

Storage and Stability:-20°C/1 year

Size:

Price/Quantity $205

Quantity:

Datasheet

SDS

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DHI2 Antibody

Western blot analysis of lysates from PC12 cells, primary antibody was diluted at 1:1000, 4°over night

Delivery

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

Telephone

408-747-0185

Fax

408-747-0145

order@assaybiotech.com

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Product Details

Product Name

DHI2 Antibody

Description

hydroxysteroid 11-beta dehydrogenase 2(HSD11B2) Homo sapiens There are at least two isozymes of the corticosteroid 11-beta-dehydrogenase, a microsomal enzyme complex responsible for the interconversion of cortisol and cortisone. The type I isozyme has both 11-beta-dehydrogenase (cortisol to cortisone) and 11-oxoreductase (cortisone to cortisol) activities. The type II isozyme, encoded by this gene, has only 11-beta-dehydrogenase activity. In aldosterone-selective epithelial tissues such as the kidney, the type II isozyme catalyzes the glucocorticoid cortisol to the inactive metabolite cortisone, thus preventing illicit activation of the mineralocorticoid receptor. In tissues that do not express the mineralocorticoid receptor, such as the Placenta and testis, it protects cells from the growth-inhibiting and/or pro-apoptotic effects of cortisol, particularly during embryonic development. Mutations in this gene cause the syndrome of apparent mine

Catalog No

C43438

Reactivity

Human, Rat, Mouse

Applications

WB, ELISA

Modification

Unmodified/Total

Source

Polyclonal Rabbit

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Storage and Stability

-20°C/1 year

Other Name

Molecular Weight (Da)

Gene Name

HSD11B2 HSD11K

Protein Name

Corticosteroid 11-beta-dehydrogenase isozyme 2 (EC 1.1.1.-) (11-beta-hydroxysteroid dehydrogenase type 2) (11-DH2) (11-beta-HSD2) (11-beta-hydroxysteroid dehydrogenase type II) (-HSD11 type II) (NAD-dependent 11-beta-hydroxysteroid dehydrogenase) (11-beta-HSD)

Human Gene ID

3291

Human Swiss Prot No.

P80365

Immunogen

Synthesized peptide derived from part region of human protein

Specificity

DHI2 Polyclonal Antibody detects endogenous levels of protein.

Formulation

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.