HUWE1 Antibody (C44150) | Assay Biotech Inc.

HUWE1 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C44150

Reactivity:Human,Mouse

Applications:IHC-p,IF(paraffin section)

Modification:Unmodified/Total

Source:Polyclonal Rabbit

Storage and Stability:-20°C/1 year

Size:

Price/Quantity $205

Quantity:

Datasheet

SDS

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HUWE1 Antibody

Delivery

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

Telephone

408-747-0185

Fax

408-747-0145

order@assaybiotech.com

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Product Details

Product Name

HUWE1 Antibody

Description

This gene encodes a protein containing a C-terminal HECT (E6AP type E3 ubiquitin protein ligase) domain that functions as an E3 ubiquitin ligase. The encoded protein is required for the ubiquitination and subsequent degradation of the anti-apoptotic protein Mcl1 (myeloid cell leukemia sequence 1 (BCL2-related)). This protein also ubiquitinates the p53 tumor suppressor, core histones, and DNA polymerase beta. Mutations in this gene are associated with Turner type X-linked syndromic mental retardation. [provided by RefSeq, Aug 2013]

Catalog No

C44150

Reactivity

Human, Mouse

Applications

IHC-p, IF(paraffin section)

Modification

Unmodified/Total

Source

Polyclonal Rabbit

Dilution

IHC-p 1:50-300

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Storage and Stability

-20°C/1 year

Other Name

Molecular Weight (Da)

Gene Name

HUWE1 KIAA0312 KIAA1578 UREB1 HSPC272

Protein Name

E3 ubiquitin-protein ligase HUWE1 (EC 6.3.2.-) (ARF-binding protein 1) (ARF-BP1) (HECT, UBA and WWE domain-containing protein 1) (Homologous to E6AP carboxyl terminus homologous protein 9) (HectH9) (Large structure of UREB1) (LASU1) (Mcl-1 ubiquitin ligase E3) (Mule) (Upstream regulatory element-binding protein 1) (URE-B1) (URE-binding protein 1)

Human Gene ID

10075

Human Swiss Prot No.

Q7Z6Z7

Immunogen

Synthesized peptide derived from part region of human protein

Specificity

HUWE1 Polyclonal Antibody detects endogenous levels of protein.

Formulation

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.