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MICA Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C44754
Reactivity:Human,Rat,Mouse
Applications:WB,ELISA
Modification:Unmodified/Total
Source:Polyclonal,Rabbit,IgG
Storage and Stability:Store at -20°C/1 year

$205
Product Details
Product Name
MICA Antibody
Description
This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2014],
Catalog No
C44754
Reactivity
Human, Rat, Mouse
Source
Polyclonal, Rabbit,IgG
Modification
Unmodified/Total
Applications
WB, ELISA
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
Molecular Weight (Da or kDa)
Gene Name
MICA PERB11.1
Protein Name
MHC class I polypeptide-related sequence A (MIC-A)
Human Gene ID
100507436
Human Swiss Prot No.
Q29983
Immunogen
Synthesized peptide derived from human protein . at AA range: 30-110
Specificity
MICA Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
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