OAZ3 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C45199

Reactivity:Human,Rat,Mouse

Applications:WB,ELISA

Modification:Unmodified/Total

Source:Polyclonal Rabbit

Storage and Stability:-20°C/1 year

Size:

Price/Quantity $205

Quantity:

Datasheet

SDS

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OAZ3 Antibody

Western blot analysis of lysates from A431 cells, primary antibody was diluted at 1:1000, 4°over night

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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408-747-0185

Fax

408-747-0145

order@assaybiotech.com

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Product Details

Product Name

OAZ3 Antibody

Description

The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis; thus, completing the auto-regulatory circuit. This gene encodes antizyme 3, the third member of the antizyme family. Like antizymes 1 and 2, antizyme 3 inhibits ODC activity and polyamine uptake; however, it does not stimulate ODC degradation. Also, while antizymes 1 and 2 have broad tissue distribution, expression of antizyme 3 is restricted to haploid germ cells in testis, suggesting a distinct role for this antizyme in spermiogenesis. Antizyme 3 gene knockout studies showed that ho

Catalog No

C45199

Reactivity

Human, Rat, Mouse

Applications

WB, ELISA

Modification

Unmodified/Total

Source

Polyclonal Rabbit

Dilution

WB 1:500-2000 ELISA 1:5000-20000