PTN13 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C45715

Reactivity:Human,Rat,Mouse

Applications:IHC-p,IF(paraffin section)

Modification:Unmodified/Total

Source:Polyclonal Rabbit

Storage and Stability:-20°C/1 year

Size:

Price/Quantity $205

Quantity:

Datasheet

SDS

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PTN13 Antibody

Delivery

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

Telephone

408-747-0185

Fax

408-747-0145

order@assaybiotech.com

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Product Details

Product Name

PTN13 Antibody

Description

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to Plasma membrane and cytoskeletal elements. This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha through the PDZ domains. This suggests it has a role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathways. Four alternatively spliced transcript variants, which encode distinct proteins, ha

Catalog No

C45715

Reactivity

Human, Rat, Mouse

Applications

IHC-p, IF(paraffin section)

Modification

Unmodified/Total

Source

Polyclonal Rabbit

Dilution

IHC-p 1:50-300

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Storage and Stability

-20°C/1 year

Other Name

Molecular Weight (Da)

Gene Name

PTPN13 PNP1 PTP1E PTPL1

Protein Name

Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1) (PTP-BAS) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (Protein-tyrosine phosphatase PTPL1)

Human Gene ID

5783

Human Swiss Prot No.

Q12923

Immunogen

Synthesized peptide derived from part region of human protein

Specificity

PTN13 Polyclonal Antibody detects endogenous levels of protein.

Formulation

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.