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Primary Antibodies
Anti-Human TCL1 (ABT378) Mouse Monoclonal Antibody
Anti-Human TCL1 (ABT378) Mouse Monoclonal Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: V0463
Reactivity:Human
Application:IHC
Modification:Unmodified/ Total
Source:Monoclonal Mouse
Storage and Stability:Stable at -20°C for at least 1 year.

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Immunohistochemical
Sample Sized mAbs 5477
Pathology Grade Abs
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Anti-Human TCL1 (ABT378) Mouse Monoclonal Antibody

Human diffuse large B-cell lymphoma tissue was stained with Anti-TCL1 (ABT378) Antibody

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Product Details
Product Name
Anti-Human TCL1 (ABT378) Mouse Monoclonal Antibody
Description
Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998 [PubMed 9520462]). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730) (Laine et al., 2000 [PubMed 10983986]).[supplied by OMIM, Jul 2010],
Catalog No
V0463
Reactivity
Human
Application
IHC
Modification
Unmodified/ Total
Source
Monoclonal Mouse
Storage and Stability
Stable at -20°C for at least 1 year.
Other Name
Anti TCL1A, Lymphoma/leukemia, T-cell, Oncogene TCL-1, Oncogene TCL1, P14 TCL1, P14 TCL1 protein, Protein p14 TCL1, T cell leukemia 1, T cell lymphoma 1, T cell lymphoma 1A, T-cell leukemia/lymphoma 1A, T-cell leukemia/lymphoma protein 1A, TCL 1 protein, TCL1, TCL1 oncogene, TCL1 PEN, Tcl1a, TCL1A, TCL1A_HUMAN
Gene Name
TCL1A
UniProtKB
P56279
Clone ID
ABT378
Isotype
IgG2b, Kappa
Localization
Cytoplasmic, Nuclear
Positive Tissue Control
Tonsil/ Appendix
Specificity
The antibody can specifically recognize human TCL1 protein.
Formulation
PBS, pH7.2, 0.03% Proclin 300, 50% glycerol
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Primary Antibodies

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    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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