Anti-Human Melanoma gp100 (ABT255) Mouse Monoclonal Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: V0440

Reactivity:Human

Application:IHC

Modification:Unmodified/ Total

Source:Monoclonal Mouse

Storage and Stability:Stable at -20°C for at least 1 year.

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Datasheet

SDS

Immunohistochemical

Sample Sized mAbs 5477

Pathology Grade Abs

Anti-Human Melanoma gp100 (ABT255) Mouse Monoclonal Antibody

Human malignant mesothelioma tissue was stained with Anti-PMEL (ABT255) Antibody

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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408-747-0185

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408-747-0145

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Product Details

Product Name

Anti-Human Melanoma gp100 (ABT255) Mouse Monoclonal Antibody

Description

This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011],

Catalog No

V0440

Reactivity

Human

Application

IHC

Modification

Unmodified/ Total

Source

Monoclonal Mouse

Storage and Stability

Stable at -20°C for at least 1 year.

Other Name

95 kDa melanocyte specific secreted glycoprotein, 95 kDa melanocyte-specific secreted glycoprotein, D12S53E, gp100, M-beta, ME20, ME20 M/ME20 S, ME20-M, ME20-S, ME20M, ME20M/ME20S, ME20S, Melanocyte lineage specific antigen GP100, Melanocyte protein mel 17, Melanocyte protein Pmel 17, Melanocyte protein Pmel 17 precursor, Melanocytes lineage-specific antigen GP100, Melanoma associated ME20 antigen, Melanoma gp100, Melanoma-associated ME20 antigen, Melanosomal matrix protein 17, Melanosomal matrix protein17, P1, p100, p26, PMEL 17, PMEL, PMEL_HUMAN, PMEL17, Premelanosome protein, Secreted melanoma-associated ME20 antigen, SI, SIL, SILV, Silver (mouse homolog) like, Silver homolog, Silver locus protein homolog, Silver, mouse, homolog of

Gene Name

PMEL

UniProtKB

P40967

Clone ID

ABT255

Isotype

IgG1, Kappa

Localization

Cytoplasmic

Positive Tissue Control

Skin/ Melanoma