p120 catenin (AB1263) mouse mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: V0424

Species Reactivity:Human; Mouse; Rat;

Application:Immunohistochemistry (IHC)

Host:Mouse

Clonality:Monoclonal

Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

Size:

Price/Quantity $75

Quantity:

Datasheet

SDS

Pathological Grade Antibodies

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p120 catenin (AB1263) mouse mAb

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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408-747-0185

Fax

408-747-0145

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Product Details

Product Name

p120 catenin (AB1263) mouse mAb

Description

α-Catenin、 β-Catenin、 γ-catenin and p120 catenin are members of the connexin family and mediate intercellular adhesion together with E-cadherin. P120 catenin binds to the near membrane region of E-cadherin to form a complex, which is stable and closely linked. In lobular breast cancer, E-cadherin deficiency resulted in the accumulation of p120 catenin in the cytoplasm, while in ductal breast cancer, p120 catenin in the membrane decreased and there was no accumulation of p120 catenin in the cytoplasm. Therefore, it can be used to distinguish lobular carcinoma from ductal carcinoma. Studies have shown that p120 catenin in the cytoplasm of gastric and colon cancer is related to poor adhesion of cancer cells.

Catalog No

V0424

Species Reactivity

Human; Mouse; Rat;

Clonality

Monoclonal

Host

Mouse

Modifcation

Unmodified

Clone

AB1263

Isotype

IgG2b, kappa

Application

Immunohistochemistry (IHC)

Application Dilutions

IHC, 1:50-1:100

Immunogen

A synthetic peptide corresponding to the amino acid region 600 - 700 of the human p120 catenin protein.

Specificity

The antibody can specifically recognize human p120 catenin protein.

Formulation

The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.

Purification

The antibody was purified by affinity chromatography using a specific immunogen.

Storage and Stability

Store at-20℃. Avoid freeze / thaw cycles.

Gene Name

CTNND1

Gene ID

1500

Human swiss

O60716

Protein Name

p120 catenin

Synonyms

Cadherin associated Src substRate, Cadherin-associated Src substRate, CAS, Catenin (cadherin associated protein) delta 1, Catenin delta 1, Catenin delta, Catenin delta-1, CTND1_HUMAN, CTNND 1, CTNND, CTNND1, delta 1 Catenin, KIAA0384, p120, P120 CAS, p120 catenin, P120 CTN, p120 (cas) , p120 (ctn) , P120CAS, P120CTN