Anti-Human MDR1 (ABT252) Mouse Monoclonal Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: V0392

Reactivity:Human

Application:IHC,WB

Modification:Unmodified/ Total

Source:Monoclonal Mouse

Storage and Stability:Stable at -20°C for at least 1 year.

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Datasheet

SDS

Immunohistochemical

Sample Sized mAbs 5477

Pathology Grade Abs

Anti-Human MDR1 (ABT252) Mouse Monoclonal Antibody

Hela whole cell lysates were separated by 6% SDS-PAGE, and the membrane was blotted with anti-MDR1(ABT252)antibody. The HRP-conjugated Goat anti-Mouse IgG(H + L) antibody was used to detect the antibody. Lane 1: Hela Predicted band size: 141kDa Observed band size: 120kDa

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Product Details

Product Name

Anti-Human MDR1 (ABT252) Mouse Monoclonal Antibody

Description

The membrane-associated protein encoded byThis gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance.The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. [provided by RefSeq, Jul 2008],

Catalog No

V0392

Reactivity

Human

Application

IHC,WB

Modification

Unmodified/ Total

Source

Monoclonal Mouse

Storage and Stability

Stable at -20°C for at least 1 year.

Other Name

ABC20, ABCB1, ATP binding cassette, sub family B (MDR/TAP), member 1, ATP-binding cassette sub-family B member 1, CD243, CLCS, Colchicin sensitivity, Doxorubicin resistance, GP170, MDR1, MDR1_HUMAN, Multidrug resistance 1, Multidrug resistance protein 1, P glycoprotein 1, P gp, P-glycoprotein 1, PGY1

Gene Name

ABCB1

UniProtKB

P08183

Clone ID

ABT252

Isotype

IgG1, Kappa

Localization

Membranous

Positive Tissue Control

Kindey