Anti-Human Factor XIIIa (ABT170) Mouse Monoclonal Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: V0335

Reactivity:Human

Application:IHC,WB

Modification:Unmodified/ Total

Source:Monoclonal Mouse

Storage and Stability:Stable at -20°C for at least 1 year.

Size:

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Datasheet

SDS

Immunohistochemical

Sample Sized mAbs 5477

Pathology Grade Abs

Anti-Human Factor XIIIa (ABT170) Mouse Monoclonal Antibody

Human dermatofibrosarcoma protuberans tissue was stained with Anti-Factor XIIIa (ABT170) Antibody

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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408-747-0185

Fax

408-747-0145

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Product Details

Product Name

Anti-Human Factor XIIIa (ABT170) Mouse Monoclonal Antibody

Description

This gene encodes the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. It also crosslinks alpha-2-plasmin inhibitor, or

Catalog No

V0335

Reactivity

Human

Application

IHC,WB

Modification

Unmodified/ Total

Source

Monoclonal Mouse

Storage and Stability

Stable at -20°C for at least 1 year.

Other Name

bA525O21.1 (coagulation factor XIII, A1 polypeptide), Coagulation factor XIII A chain, Coagulation factor XIII A1 polypeptide, Coagulation factor XIII A1 subunit, Coagulation factor XIII, A polypeptide, Coagulation factor XIIIa, F13A, F13A_HUMAN, F13a1, Factor XIIIA, Fibrin stabilizing factor, A subunit, Fibrinoligase, FSF, A subunit, Protein glutamine gamma glutamyltransferase A chain, Protein-glutamine gamma-glutamyltransferase A chain, TGase, Transglutaminase A chain, Transglutaminase, plasma, Transglutaminase. plasma

Gene Name

F13A1

UniProtKB

P00488

Clone ID

ABT170

Isotype

IgG1, Kappa

Localization

Cytoplasmic

Positive Tissue Control

Tonsil

Specificity

The antibody can specifically recognize human Factor XIIIa protein. In western blotting of A431 cell lysates, there shows a 100 kDa band detected by the antibody.

Formulation

PBS, pH7.2, 0.03% Proclin 300, 50% glycerol