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Anti-Human Beta-catenin (ABT-Catenin) Mouse Monoclonal Antibody
Anti-Human Beta-catenin (ABT-Catenin) Mouse Monoclonal Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: V0154
Reactivity:Human
Application:IHC,WB
Modification:Unmodified/ Total
Source:Monoclonal Mouse
Storage and Stability:Stable at -20°C for at least 1 year.

$Sample Size
Product Details
Product Name
Anti-Human Beta-catenin (ABT-Catenin) Mouse Monoclonal Antibody
Description
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016],
Catalog No
V0154
Reactivity
Human
Application
IHC,WB
Modification
Unmodified/ Total
Source
Monoclonal Mouse
Storage and Stability
Stable at -20°C for at least 1 year.
Other Name
b-catenin, Beta catenin, Beta-catenin, Cadherin associated protein, Catenin (cadherin associated protein), beta 1, 88 kDa, Catenin beta 1, Catenin beta-1, CATNB, CHBCAT, CTNB1_HUMAN, CTNNB, CTNNB1, DKFZp686D02253, FLJ25606, FLJ37923, OTTHUMP00000162082, OTTHUMP00000165222, OTTHUMP00000165223, OTTHUMP00000209288, OTTHUMP00000209289
Gene Name
CTNNB1
UniProtKB
P35222
Clone ID
ABT-Catenin
Isotype
IgG2b, Kappa
Localization
Membranous
Positive Tissue Control
Colon/Appendix/Liver
Specificity
The antibody can specifically recognize human β- Catenin protein. In western blotting of Hela, A431 and HEK293 cell lysates, the antibody labels β- Cateninn, no reaction with α or γ-catenin.
Formulation
PBS, pH7.2, 0.03% Proclin 300, 50% glycerol
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Publications (2)