aurora kinase A(AURKA) Homo sapiens. The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],
Catalog No
N0047
Reactivity
Human,Rat,Monkey
Applications
WB,IHC-p,IF(paraffin section),ELISA
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Western Blot analysis using ARK-1 Monoclonal Antibody against HEK293 (1). Sw620 (2). MCF-7 (3). Jurkat (4). HeLa (5). HepG2 (6). Cos7 (7) and PC-12 (8) cell lysate.
