calnexin(CANX) Homo sapiens. This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008],
Catalog No
N0088
Reactivity
Human
Applications
WB,IF/ICC,ELISA
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Purification
Affinity purification
Concentration
Storage and Stability
-20°C/1 year
Other Name
CANX; Calnexin; IP90; Major histocompatibility complex class I antigen-binding protein p88; p90
Molecular Weight (Da)
Gene Name
CANX
Protein Name
Calnexin
Human Gene ID
821
Human Swiss Prot No.
P27824
Immunogen
Synthetic peptide corresponding to aa (CEAAEERPWLWVVYILTVAL) of human Calnexin, conjugated to KLH.
Specificity
Calnexin Monoclonal Antibody detects endogenous levels of Calnexin protein.
