Cbl Monoclonal Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: N0095

Reactivity:Human,Mouse,Rat

Applications:WB,IHC-p,IF/ICCFCM,ELISA

Modification:Unmodfied/ Total

Source:Monoclonal Mouse

Storage and Stability:-20°C/1 year

Size:

Price/Quantity $210

Quantity:

Datasheet

SDS

Signaling Intermediates

Buy One Get One

Cbl Monoclonal Antibody

Western Blot analysis using Cbl Monoclonal Antibody against RAJI (1). RAW264.7 (2). K562 (3). SKBR-3 (4). 3T3-L1 (5). THP-1 (6) and PC-12 (7) cell lysate.

Delivery

Freight Charges

Utilize our shipping calculator at checkout to view

Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

Telephone

408-747-0185

Fax

408-747-0145

order@assaybiotech.com

Promotions

Product Details

Product Name

Cbl Monoclonal Antibody

Description

Cbl proto-oncogene(CBL) Homo sapiens This gene is a proto-oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates and target them for proteasome degradation. As such it functions as a negative regulator of many signal transduction pathways. This gene has been found to be mutated or translocated in many cancers including acute myeloid leukaemia, and expansion of CGG repeats in the 5' UTR has been associated with Jacobsen syndrome. Mutations in this gene are also the cause of Noonan syndrome-like disorder. [provided by RefSeq, Jul 2016],

Catalog No

N0095

Reactivity

Human,Mouse,Rat

Applications

WB,IHC-p,IF/ICC,FCM,ELISA

Modification

Unmodfied/ Total

Source

Monoclonal Mouse

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. Immunofluorescence: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. Not yet tested in other applications.

Purification

Affinity purification

Concentration

Storage and Stability

-20°C/1 year

Other Name

CBL; CBL2; RNF55; E3 ubiquitin-protein ligase CBL; Casitas B-lineage lymphoma proto-oncogene; Proto-oncogene c-Cbl; RING finger protein 55; Signal transduction protein CBL

Molecular Weight (Da)

Gene Name

CBL

Protein Name

E3 ubiquitin-protein ligase CBL

Human Gene ID

867

Human Swiss Prot No.

P22681

Immunogen

Purified recombinant fragment of human Cbl expressed in E. Coli.

Specificity