activated leukocyte cell adhesion molecule(ALCAM)Homo sapiens. This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Aug 2011],
Catalog No
N0105
Reactivity
Human
Applications
IHC-p,IF(paraffin section),ELISA
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
Immunohistochemistry: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Immunohistochemistry analysis of paraffin-embedded human ovary carcinoma (A). kidney carcinoma (B). lung carcinoma (C) and breast carcinoma (D). showing cytoplasmic and membrane localization with DAB staining using CD166 Monoclonal Antibody.