cerberus 1, DAN family BMP antagonist(CER1) Homo sapiens. This gene encodes a cytokine member of the cysteine knot superfamily, characterized by nine conserved cysteines and a cysteine knot region. The cerberus-related cytokines, together with Dan and DRM/Gremlin, represent a group of bone morphogenetic protein (BMP) antagonists that can bind directly to BMPs and inhibit their activity. [provided by RefSeq, Jul 2008],
Catalog No
N0148
Reactivity
Human
Applications
WB,IHC-p,IF(paraffin section),ELISA
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Purification
Affinity purification
Concentration
Storage and Stability
-20°C/1 year
Other Name
CER1; DAND4; Cerberus; Cerberus-related protein; DAN domain family member 4
Molecular Weight (Da)
Gene Name
CER1
Protein Name
Cerberus
Human Gene ID
9350
Human Swiss Prot No.
O95813
Immunogen
Purified recombinant fragment of human Cerberus expressed in E. Coli.
Specificity
Cerberus Monoclonal Antibody detects endogenous levels of Cerberus protein.
Immunohistochemistry analysis of paraffin-embedded human gastric cancer (left) and normal gastric tissues (right) with DAB staining using Cerberus Monoclonal Antibody.