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Cortactin Monoclonal Antibody
Cortactin Monoclonal Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: N0160
Reactivity:Human,Mouse
Applications:WB,IHC-p,IF(paraffin section),ELISA
Modification:Unmodfied/ Total
Source:Monoclonal Mouse
Storage and Stability:-20°C/1 year

$210
Product Details
Product Name
Cortactin Monoclonal Antibody
Description
cortactin(CTTN) Homo sapiens This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq, May 2010],
Catalog No
N0160
Reactivity
Human,Mouse
Applications
WB,IHC-p,IF(paraffin section),ELISA
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Purification
Affinity purification
Concentration
Storage and Stability
-20°C/1 year
Other Name
CTTN; EMS1; Src substrate cortactin; Amplaxin; Oncogene EMS1
Molecular Weight (Da)
Gene Name
CTTN
Protein Name
Src substrate cortactin
Human Gene ID
2017
Human Swiss Prot No.
Q14247
Immunogen
Purified recombinant fragment of human Cortactin expressed in E. Coli.
Specificity
Cortactin Monoclonal Antibody detects endogenous levels of Cortactin protein.
Formulation
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
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