Crystallin-αB Monoclonal Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: N0168

Reactivity:Human

Applications:WB,IHC-p,IF(paraffin section),ELISA

Modification:Unmodfied/ Total

Source:Monoclonal Mouse

Storage and Stability:-20°C/1 year

Size:

Price/Quantity $210

Quantity:

Datasheet

SDS

Signaling Intermediates

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Crystallin-αB Monoclonal Antibody

Western Blot analysis using Crystallin-αB Monoclonal Antibody against HEK293T cells transfected with the pCMV6-ENTRY control (1) and pCMV6-ENTRY CRYAB cDNA (2).

Delivery

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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408-747-0185

Fax

408-747-0145

order@assaybiotech.com

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Product Details

Product Name

Crystallin-αB Monoclonal Antibody

Description

Mammalian lens crystallins are divided into alpha, beta, and gamma families. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone; instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. These heterogeneous aggregates consist of 30-40 subunits; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distin

Catalog No

N0168

Reactivity

Human

Applications

WB,IHC-p,IF(paraffin section),ELISA

Modification

Unmodfied/ Total

Source

Monoclonal Mouse

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Purification

Affinity purification

Concentration

Storage and Stability

-20°C/1 year

Other Name

CRYAB; CRYA2; Alpha-crystallin B chain; Alpha(B)-crystallin; Heat shock protein beta-5; HspB5; Renal carcinoma antigen NY-REN-27; Rosenthal fiber component

Molecular Weight (Da)

Gene Name

CRYAB

Protein Name

Alpha-crystallin B chain

Human Gene ID

1410

Human Swiss Prot No.

P02511

Immunogen

Purified recombinant fragment of Crystallin-αB (aa1-175) expressed in E. Coli.

Specificity