cyclin B1(CCNB1)Homo sapiens. The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. [provided by RefSeq, Jul 2008],
Catalog No
N0173
Reactivity
Human
Applications
WB,IHC-p,IF(paraffin section),ELISA
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Purification
Affinity purification
Concentration
Storage and Stability
-20°C/1 year
Other Name
CCNB1; CCNB; G2/mitotic-specific cyclin-B1
Molecular Weight (Da)
Gene Name
CCNB1
Protein Name
G2/mitotic-specific cyclin-B1
Human Gene ID
891
Human Swiss Prot No.
P14635
Immunogen
Purified recombinant fragment of human Cyclin B1 expressed in E. Coli.
Immunohistochemistry analysis of paraffin-embedded lung cancer (left) and ovary tumour tissues (right) with DAB staining using Cyclin B1 Monoclonal Antibody.