dickkopf WNT signaling pathway inhibitor 1(DKK1)Homo sapiens. This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. [provided by RefSeq, Jul 2008],
Catalog No
N0197
Reactivity
Human
Applications
WB,ELISA
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Purification
Affinity purification
Concentration
Storage and Stability
-20°C/1 year
Other Name
DKK1; Dickkopf-related protein 1; Dickkopf-1; Dkk-1; hDkk-1; SK
Molecular Weight (Da)
Gene Name
DKK1
Protein Name
Dickkopf-related protein 1
Human Gene ID
22943
Human Swiss Prot No.
O94907
Immunogen
Purified recombinant fragment of Dkk-1 expressed in E. Coli.
Specificity
Dkk-1 Monoclonal Antibody detects endogenous levels of Dkk-1 protein.
