dickkopf WNT signaling pathway inhibitor 3(DKK3)Homo sapiens. This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008],
Catalog No
N0198
Reactivity
Human,Monkey
Applications
WB,FCM,ELISA
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
Western Blot: 1/500 - 1/2000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. Not yet tested in other applications.
Purification
Affinity purification
Concentration
Storage and Stability
-20°C/1 year
Other Name
DKK3; REIC; Dickkopf-related protein 3; Dickkopf-3; Dkk-3; hDkk-3
Molecular Weight (Da)
Gene Name
DKK3
Protein Name
Dickkopf-related protein 3
Human Gene ID
27122
Human Swiss Prot No.
Q9UBP4
Immunogen
Purified recombinant fragment of human Dkk-3 expressed in E. Coli.
Specificity
Dkk-3 Monoclonal Antibody detects endogenous levels of Dkk-3 protein.
