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Arrestin-β-2 Monoclonal Antibody
Arrestin-β-2 Monoclonal Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: N0665
Reactivity:Human,Mouse,Rat,Pig
Applications:WB,IF/ICC
Modification:Unmodfied/ Total
Source:Monoclonal Mouse
Storage and Stability:-20°C/1 year

$210
Product Details
Product Name
Arrestin-β-2 Monoclonal Antibody
Description
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012],
Catalog No
N0665
Reactivity
Human,Mouse,Rat,Pig
Applications
WB,IF/ICC
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
Western Blot: 1/1000 - 1/2000. Immunofluorescence: 1/100 - 1/500. Not yet tested in other applications.
Purification
Affinity purification
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
ARRB2; ARB2; ARR2; Beta-arrestin-2; Arrestin beta-2
Molecular Weight (Da)
Gene Name
ARRB2
Protein Name
Beta-arrestin-2
Human Gene ID
409
Human Swiss Prot No.
P32121
Immunogen
Purified recombinant human Arrestin-β-2 (C-terminus) protein fragments expressed in E.coli.
Specificity
Arrestin-β-2 Monoclonal Antibody detects endogenous levels of Arrestin-β-2 protein.
Formulation
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.
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