PA28γ Monoclonal Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: N0723

Reactivity:Human,Mouse,Dog,Pig

Applications:WB,IF/ICC

Modification:Unmodfied/ Total

Source:Monoclonal Mouse

Storage and Stability:-20°C/1 year

Size:

Price/Quantity $210

Quantity:

Datasheet

SDS

Signaling Intermediates

Buy One Get One

PA28γ Monoclonal Antibody

Western Blot analysis using PA28γ Monoclonal Antibody against HepG2. Jurkat. K562 cell lysate.

Delivery

Freight Charges

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

Telephone

408-747-0185

Fax

408-747-0145

order@assaybiotech.com

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Product Details

Product Name

PA28γ Monoclonal Antibody

Description

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) o

Catalog No

N0723

Reactivity

Human,Mouse,Dog,Pig

Applications

WB,IF/ICC

Modification

Unmodfied/ Total

Source

Monoclonal Mouse

Dilution

Western Blot: 1/1000 - 1/2000. Immunofluorescence: 1/100 - 1/500. Not yet tested in other applications.

Purification

Affinity purification

Concentration

1 mg/ml

Storage and Stability

-20°C/1 year

Other Name

PSME3; Proteasome activator complex subunit 3; 11S regulator complex subunit gamma; REG-gamma; Activator of multicatalytic protease subunit 3; Ki nuclear autoantigen; Proteasome activator 28 subunit gamma; PA28g; PA28gamma

Molecular Weight (Da)

Gene Name

PSME3

Protein Name

Proteasome activator complex subunit 3

Human Gene ID

10197

Human Swiss Prot No.

P61289

Immunogen

Purified recombinant human PA28γ protein fragments expressed in E.coli.

Specificity