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Primary Antibodies
RASSF1 Monoclonal Antibody
RASSF1 Monoclonal Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: N0742
Reactivity:Human
Applications:WB
Modification:Unmodfied/ Total
Source:Monoclonal Mouse
Storage and Stability:-20°C/1 year

$210
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RASSF1 Monoclonal Antibody

Western Blot analysis using RASSF1 Monoclonal Antibody against mouse liver. mouse brain lysate.

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Product Details
Product Name
RASSF1 Monoclonal Antibody
Description
This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, May 2011],
Catalog No
N0742
Reactivity
Human
Applications
WB
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
Western Blot: 1/1000 - 1/2000. Not yet tested in other applications.
Purification
Affinity purification
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
RASSF1; RDA32; Ras association domain-containing protein 1
Molecular Weight (Da)
Gene Name
RASSF1
Protein Name
Ras association domain-containing protein 1
Human Gene ID
11186
Human Swiss Prot No.
Q9NS23
Immunogen
Purified recombinant human RASSF1 protein fragments expressed in E.coli.
Specificity
RASSF1 Monoclonal Antibody detects endogenous levels of RASSF1 protein.
Formulation
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.
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Publications (1)
TDP-43 aggregation induced by oxidative stress causes global mitochondrial imbalance in ALS. NATURE STRUCTURAL & MOLECULAR BIOLOGY Nat Struct Mol Biol. 2021 Jan;28(2):132-142 WB Mouse 1:2000 N2a cell

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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