NUP98 mouse mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: N0883

Reactivity:Human

Applications:WB,IP

Modification:Unmodfied/ Total

Source:Monoclonal Mouse

Storage and Stability:-20°C/1 year

Size:

Price/Quantity $160

Quantity:

Datasheet

SDS

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NUP98 mouse mAb

Western blot detection of NUP98 in Hela.Jurkat and MCF7 cell lysates using NUP98 mouse mAb (1:1000 diluted).Predicted band size: 98kDa.Observed band size: 98kDa.

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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408-747-0185

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408-747-0145

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Product Details

Product Name

NUP98 mouse mAb

Description

Nuclear pore complexes (NPCs) regulate the transport of macromolecules between the nucleus and cytoplasm, and are composed of many polypeptide subunits, many of which belong to the nucleoporin family. This gene belongs to the nucleoporin gene family and encodes a 186 kDa precursor protein that undergoes autoproteolytic cleavage to generate a 98 kDa nucleoporin and 96 kDa nucleoporin. The 98 kDa nucleoporin contains a Gly-Leu-Phe-Gly (GLGF) repeat domain and participates in many cellular processes, including nuclear import, nuclear export, mitotic progression, and regulation of gene expression. The 96 kDa nucleoporin is a scaffold component of the NPC. Proteolytic cleavage is important for targeting of the proteins to the NPC. Translocations between this gene and many other partner genes have been observed in different leukemias. Rearrangements typically result in chimeras with the N-terminal GLGF domain of

Catalog No

N0883

Reactivity

Human

Applications

WB,IP

Modification

Unmodfied/ Total

Source

Monoclonal Mouse

Dilution

wb 1:1000

Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Storage and Stability

-20°C/1 year

Other Name

96 kDa nucleoporin;98 kDa nucleoporin;ADAR2;ADIR2;GLFG-repeat containing nucleoporin; Nuclear pore complex protein Nup96;Nuclear pore complex protein Nup98 Nup96;Nucleoporin 98kD;nucleoporin 98kDa;Nucleoporin Nup96;Nucleoporin Nup98;NUP196;NUP96;Nup98;Nup98-Nup96;NUP98_HUMAN.

Molecular Weight (Da)

Gene Name

nup98

Protein Name

Human Gene ID

4928

Human Swiss Prot No.

P52948

Immunogen

Purified recombinant human NUP98 protein fragments expressed in E.coli.

Specificity

This antibody detects endogenous levels of NUP98 and does not cross-react with related proteins.