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Primary Antibodies
CHD4 mouse mAb
CHD4 mouse mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: N0918
Reactivity:Human
Applications:WB,IP
Modification:Unmodfied/ Total
Source:Monoclonal Mouse
Storage and Stability:-20°C/1 year

$160
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CHD4 mouse mAb

Western blot detection of CHD4 in K562.HelaNE.HL-60.MOLT-4.Jurkat and 293 cell lysates using CHD4 mouse mAb (1:1000 diluted).Predicted band size:260KDa.Observed band size:260KDa.

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Product Details
Product Name
CHD4 mouse mAb
Description
chromodomain helicase DNA binding protein 4(CHD4)Homo sapiens. The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014],
Catalog No
N0918
Reactivity
Human
Applications
WB,IP
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
wb 1:1000
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
ATP dependent helicase CHD4;ATP-dependent helicase CHD4;CHD 4;CHD-4;CHD4;CHD4_HUMAN; Chromodomain helicase DNA binding protein 4;Chromodomain-helicase-DNA-binding protein 4;DKFZp686E06161;Mi 2 autoantigen 218 kDa protein;Mi 2b;Mi-2 autoantigen 218 kDa protein;Mi2 beta;Mi2-beta.
Molecular Weight (Da)
Gene Name
chd4
Protein Name
Human Gene ID
1108
Human Swiss Prot No.
Q14839
Immunogen
Purified recombinant human CHD4 protein fragments expressed in E.coli.
Specificity
This antibody detects endogenous levels of CHD4 and does not cross-react with related proteins.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (1)
A PARylation-phosphorylation cascade promotes TOPBP1 loading and RPA-RAD51 exchange in homologous recombination

Author: Jiao Zhao, Shanshan Tian, Qiushi Guo, Kaiwen Bao, Guohui Yu, Xiaodan Wang, Xilin Shen, Jieyou Zhang, Jiaxin Chen, Ying Yang, Ling Liu, Xiangchun Li, Jihui Hao, Na Yang, Zhe Liu, Ding Ai, Jie Yang, Yi Zhu, Zhi Yao, Shuai Ma

Date of Publication : 2022-05-20

Primary Antibodies

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    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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