eIF2α mouse mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: N1009

Reactivity:Human,Mouse,Rat

Applications:WB,IF/ICC,IP

Modification:Unmodfied/ Total

Source:Monoclonal Mouse

Storage and Stability:-20°C/1 year

Size:

Price/Quantity $160

Quantity:

Datasheet

SDS

Signaling Intermediates

eIF2α mouse mAb

Western blot detection of eIF2α in K562.COS7.3T3. C2C12.MCF-7.C6 and Hela cell lysates using eIF2α mouse mAb (1:1000 diluted).Predicted band size:38KDa.Observed band size:38KDa.

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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408-747-0185

Fax

408-747-0145

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Product Details

Product Name

eIF2α mouse mAb

Description

eukaryotic translation initiation factor 2 subunit alpha(EIF2S1)Homo sapiens. The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010],

Catalog No

N1009

Reactivity

Human,Mouse,Rat

Applications

WB,IF/ICC,IP

Modification

Unmodfied/ Total

Source

Monoclonal Mouse

Dilution

wb dilution 1:1000 icc dilution 1:200

Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Storage and Stability

-20°C/1 year

Other Name

Dmel\CG6376 ;Dmel_CG6376 ;drosE2F1 ;E(Sev-CycE)3A ;E(var)3-93E ;E2-promoter binding facto ;E2F 1 ;E2F transcription factor 1 ;E2F-1 ;E2f-PA ;E2f-PB ;E2f-PC ;E2F1 ;E2f1 E2F transcription factor 1 ;E2F1_HUMAN ;Evar(3)164 ;KIAA4009 ;l(3)07172 ;l(3)j3B1 ;l(3)j3C2 ;l(3)rM729 ;mKIAA4009 ;OTTHUMP00000030661 ;PBR3 ;PRB binding protein E2F 1 ;PRB-binding protein E2F-1 ;RBAP 1 ;RBAP-1 ;RBAP1 ;RBBP-3 ;RBBP3 ;RBP 3 ;RBP3 ;Retinoblastoma-associated protein 1 ;Retinoblastoma-binding protein 3 ;Transcription factor E2F1.

Molecular Weight (Da)

Gene Name

eif2s1

Protein Name

Human Gene ID

1965

Human Swiss Prot No.

P05198

Immunogen

Purified recombinant human eIF2α protein fragments expressed in E.coli.

Specificity

This antibody detects endogenous levels of eIF2α and does not cross-react with related proteins.