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Primary Antibodies
S12A1 Antibody
S12A1 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C46057
Reactivity:Human,Mouse,Rat
Applications:WB
Modification:Unmodified/Total
Source:Polyclonal,Rabbit,IgG
Storage and Stability:Store at -20°C/1 year

$205
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S12A1 Antibody

Western blot analysis of lysates from THP-1 cells, primary antibody was diluted at 1:1000, 4°over night

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Product Details
Product Name
S12A1 Antibody
Description
This gene encodes a kidney-specific sodium-potassium-chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity in humans has not been experimentally proven.[provided by RefSeq, May 2010],
Catalog No
C46057
Reactivity
Human, Mouse, Rat
Source
Polyclonal, Rabbit,IgG
Modification
Unmodified/Total
Applications
WB
Dilution
WB 1：500-2000
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
Molecular Weight (Da or kDa)
121kD
Gene Name
SLC12A1 NKCC2
Protein Name
S12A1
Human Gene ID
6557
Human Swiss Prot No.
Q13621
Immunogen
Synthesized peptide derived from human S12A1 AA range: 595-645
Specificity
This antibody detects endogenous levels of S12A1 at Human/Mouse/Rat
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (1)
Urea transporter UT-A1 as a novel drug target for hyponatremia FASEB JOURNAL Nannan Li WB Rat kidney tissue

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

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    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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