FADD mouse mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: N1048

Reactivity:Human

Applications:WB

Modification:Unmodfied/ Total

Source:Monoclonal Mouse

Storage and Stability:-20°C/1 year

Size:

Price/Quantity $160

Quantity:

Datasheet

SDS

Tumor Suppressors/Apoptosis

FADD mouse mAb

Western blot detection of FADD in A431 and Jurkat cell lysates using FADD mouse mAb (1:1000 diluted).Predicted band size:23KDa.Observed band size:23KDa.

Delivery

Freight Charges

Utilize our shipping calculator at checkout to view

Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

Telephone

408-747-0185

Fax

408-747-0145

order@assaybiotech.com

Promotions

Product Details

Product Name

FADD mouse mAb

Description

Fas associated via death domain(FADD) Homo sapiens. The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq, Jul 2008],

Catalog No

N1048

Reactivity

Human

Applications

Modification

Unmodfied/ Total

Source

Monoclonal Mouse

Dilution

wb dilution 1:1000

Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Storage and Stability

-20°C/1 year

Other Name

FADD;FADD protein;FADD_HUMAN;Fas (TNFRSF6) associated via death domain;Fas associated via death domain;Fas associating death domain containing protein;Fas associating death domain containing protein;Fas associating protein;Fas associating protein with death domain;Fas associating protein with death domain;Fas TNFRSF6 associated via death domain;FAS-associated death domain protein;FAS-associating death domain-containing protein;FasTNFRSF6 associated via death domain;FasTNFRSF6 associated via death domain; GIG 3;GIG3;Growth inhibiting gene 3 protein;Growth-inhibiting gene 3 protein;H sapiens mRNA for mediator of receptor induced toxicity;H sapiens mRNA for mediator of receptor induced toxicity;Mediator of receptor induced toxicity;Mediator of receptor induced toxicity;MGC8528;MGC8528;MORT 1;MORT1;MORT1;Protein FADD.

Molecular Weight (Da)

Gene Name

fadd

Protein Name

Human Gene ID

8772

Human Swiss Prot No.

Q13158

Immunogen

Purified recombinant human FADD protein fragments expressed in E.coli.

Specificity

This antibody detects endogenous levels of FADD and does not cross-react with related proteins.