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Primary Antibodies
Histone H3 Monoclonal Antibody(1G1)
Histone H3 Monoclonal Antibody(1G1)

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: N1302
Reactivity:Human,Mouse,Rat,Yeast
Applications:WB,IHC-p,IF/ICCIP
Modification:Unmodfied/ Total
Source:Monoclonal Mouse
Storage and Stability:-20°C/1 year

$200
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Histone H3 Monoclonal Antibody(1G1)

Western blot analysis of 1) Hela. 2) Raw. 3) Mouse Brain Tissue. 4) Rat Brain Tissue. diluted at 1:5000. cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003.Inventbiotech.MN.USA).

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Product Details
Product Name
Histone H3 Monoclonal Antibody(1G1)
Description
histone cluster 1 H3 family member a(HIST1H3A) Homo sapiens. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015],
Catalog No
N1302
Reactivity
Human,Mouse,Rat,Yeast
Applications
WB,IHC-p,IF/ICC,IP
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
WB: 1:2000-5000 IF:1:100-500 IP:1:200 IHC 1:50-300
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Concentration
Storage and Stability
-20°C/1 year
Other Name
HIST1H3A; H3FA; HIST1H3B; H3FL; HIST1H3C; H3FC; HIST1H3D; H3FB; HIST1H3E; H3FD; HIST1H3F; H3FI; HIST1H3G; H3FH; HIST1H3H; H3FK; HIST1H3I; H3FF; HIST1H3J; H3FJ; Histone H3.1; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l; HIST2H3A; HIST2H3C; H3F2; H3FM; HIST2H3D; Histone H3.2; Histone H3/m; Histone H3/o; H3F3A; H3.3A; H3F3; PP781; H3F3B; H3.3B; Histone H3.3
Molecular Weight (Da)
15273
Gene Name
HIST1H3A/HIST1H3B/HIST1H3C/HIST1H3D/HIST1H3E/HIST1H3F/HIST1H3G/HIST1H3H/HIST1H3I/HIST1H3J/HIST2H3A/HIST2H3C/HIST2H3D/H3F3A/H3F3B
Protein Name
Histone H3.1/Histone H3.2/Histone H3.3
Human Gene ID
8350/8351/8352/8353/8354/8355/8356/8357/8358/8968
Human Swiss Prot No.
P68431/Q71DI3/P84243
Immunogen
Recombinant Protein of Histone H3
Specificity
The antibody detects endogenous Histone H3 protein.
Formulation
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
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Publications (8)
A PARylation-phosphorylation cascade promotes TOPBP1 loading and RPA-RAD51 exchange in homologous recombination

Author: Jiao Zhao, Shanshan Tian, Qiushi Guo, Kaiwen Bao, Guohui Yu, Xiaodan Wang, Xilin Shen, Jieyou Zhang, Jiaxin Chen, Ying Yang, Ling Liu, Xiangchun Li, Jihui Hao, Na Yang, Zhe Liu, Ding Ai, Jie Yang, Yi Zhu, Zhi Yao, Shuai Ma

Date of Publication : 2022-05-20

Lrwd1 impacts cell proliferation and the silencing of repetitive DNA elements

Author: Tze Zhen Evangeline Kang, Yi Ching Esther Wan, Zhiguo Zhang, Kui Ming Chan

Date of Publication : 2022-04-22

IL-5 enhances the resistance of Actinobacillus pleuropneumoniae infection in mice through maintaining appropriate levels of lung M2, PMN-II and highly effective neutrophil extracellular traps

Author: Peiru Chen, Chuntong Bao, Rining Zhu, Jun Wang, Junhui Zhu, Ziheng Li, Fengyang Li, Jingmin Gu, Xin Feng, Na Li, Liancheng Lei

Date of Publication : 2022-04-19

β2SP/TET2 complex regulates gene 5hmC modification after cerebral ischemia

Author: Xiaohua Ma, Meng Zhang, Rui Yan, Hainan Wu, Bo Yang, Zhigang Miao

Date of Publication : 2021-11-19

The elevated transcription of ADAM19 by the oncohistone H2BE76K contributes to oncogenic properties in breast cancer

Author: Tze Zhen Evangeline Kang, Lina Zhu, Du Yang, Dongbo Ding, Xiaoxuan Zhu, Yi Ching Esther Wan, Jiaxian Liu, Saravanan Ramakrishnan, Landon Long Chan, Siu Yuen Chan, Xin Wang, Haiyun Gan, Junhong Han, Toyotaka Ishibashi, Qing Li, Kui Ming Chan

Date of Publication : 2021-01-01

TLR4 upregulates CBS expression through NF-κB activation in a rat model of irritable bowel syndrome with chronic visceral hypersensitivity

Author: Bo Yuan, Wei-Hong Tang, Li-Juan Lu, Yuan Zhou, Hong-Yan Zhu, You-Lang Zhou, Hong-Hong Zhang, Chuang-Ying Hu, Guang-Yin Xu

Date of Publication : 2015-07-28

α-Hederin Inhibits the Proliferation of Hepatocellular Carcinoma Cells via Hippo-Yes-Associated Protein Signaling Pathway.

Author: Tongqing Chen, Dongdong Sun, Qijuan Wang, Tingting Zhou, Jiani Tan, Changliang Xu, Haibo Cheng，Weixing Shen

Date of Publication : 44623

Disrupting PHF8-TOPBP1 connection elicits a breast tumor-specific vulnerability to chemotherapeutics

Author: Shuai Ma, Jieyou Zhang, Qiushi Guo, Cheng Cao, Kaiwen Bao, Ling Liu, Charlie Degui Chen, Zhe Liu, Jie Yang, Na Yang, Zhi Yao, Lei Shi

Date of Publication : 44578

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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