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Primary Antibodies
IDE Monoclonal Antibody(3H4)
IDE Monoclonal Antibody(3H4)

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: N1348
Reactivity:Human
Applications:WB,IHC-p,IF/ICC
Modification:Unmodfied/ Total
Source:Monoclonal Mouse
Storage and Stability:-20°C/1 year

$160
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IDE Monoclonal Antibody(3H4)

Western blot analysis of 1) Hela. 2) HepG2. diluted at 1:2000

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Fax
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Email
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Product Details
Product Name
IDE Monoclonal Antibody(3H4)
Description
This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been describe
Catalog No
N1348
Reactivity
Human
Applications
WB,IHC-p,IF/ICC,
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
WB: 1:1000 IF 1:200 IHC 1:50-300
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Concentration
Storage and Stability
-20°C/1 year
Other Name
IDE; Insulin-degrading enzyme; Abeta-degrading protease; Insulin protease; Insulinase; Insulysin
Molecular Weight (Da)
Gene Name
IDE
Protein Name
Insulin-degrading enzyme
Human Gene ID
3416
Human Swiss Prot No.
P14735
Immunogen
Synthetic Peptide of IDE
Specificity
The antibody detects endogenous IDE proteins.
Formulation
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
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Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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