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Primary Antibodies
Cleaved PARP Monoclonal Antibody(Mix)
Cleaved PARP Monoclonal Antibody(Mix)

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: N1410
Reactivity:Human
Applications:IF/ICC,WB,IHC-p
Modification:Unmodfied/ Total
Source:Monoclonal Mouse
Storage and Stability:-20°C/1 year

$160
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Cleaved PARP Monoclonal Antibody(Mix)

Western blot analysis of Jurkat. diluted at 1:3000. cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003.Inventbiotech.MN.USA).

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Product Details
Product Name
Cleaved PARP Monoclonal Antibody(Mix)
Description
poly(ADP-ribose) polymerase 1(PARP1) Homo sapiens. This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008],
Catalog No
N1410
Reactivity
Human
Applications
IF/ICC,WB,IHC-p,
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
IF: 1:50-200 WB: 1:2000-5000 IHC 1:50-300
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Concentration
Storage and Stability
-20°C/1 year
Other Name
PARP1; ADPRT; PPOL; Poly [ADP-ribose] polymerase 1; PARP-1; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD(+) ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose] synthase 1
Molecular Weight (Da)
Gene Name
PARP1
Protein Name
Poly [ADP-ribose] polymerase 1
Human Gene ID
142
Human Swiss Prot No.
P09874
Immunogen
Synthetic Peptide of Cleaved PARP
Specificity
The antibody detects endogenous pro and active PARP protein.
Formulation
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
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Publications (3)
Sodium butyrate induces autophagic apoptosis of nasopharyngeal carcinoma cells by inhibiting AKT/mTOR signaling

Author: Wei Huang, Chong Zeng, Jie Liu, Li Yuan, Weidong Liu, Lei Wang, Hecheng Zhu, Yang Xu, Yi Luo, Dan Xie, Xingjun Jiang, Caiping Ren

Date of Publication : 2019-04-22

DLC-1 induces mitochondrial apoptosis and epithelial mesenchymal transition arrest in nasopharyngeal carcinoma by targeting EGFR/Akt/NF-κB pathway

Author: Huang, Wei, Liu, Jie, Feng, Xiangling, Chen, Huan, Zeng, Liang, Huang, Guoling, Liu, Weidong, Wang, Lei, Jia, Wei, Chen, Jiawen, Ren, Caiping

Date of Publication : 2015-03-17

Pivotal roles of p53 transcription-dependent and -independent pathways in manganese-induced mitochondrial dysfunction and neuronal apoptosis

Author: Chunhua Wan, Xa Ma, Shangshi Shi, Jianya Zhao, Xiaoke Nie, Jingling Han, Jing Xiao, Xiaoke Wang, Shengyang Jiang, Junkang Jiang

Date of Publication : 2014-10-28

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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