NF κB P50 Mouse mAb(5D2)

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: N1488

Reactivity:Human

Applications:IHC-p,WB

Modification:Unmodfied/ Total

Source:Monoclonal Mouse

Storage and Stability:-20°C/1 year

Size:

Price/Quantity $160

Quantity:

Datasheet

SDS

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NF κB P50 Mouse mAb(5D2)

Western blot analysis of MCF7 Cell Lysate using NF κB P50Mouse Monoclonal mAb diluted at 1:1.000.

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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408-747-0185

Fax

408-747-0145

order@assaybiotech.com

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Product Details

Product Name

NF κB P50 Mouse mAb(5D2)

Description

nuclear factor kappa B subunit 1(NFKB1) Homo sapiens This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isof

Catalog No

N1488

Reactivity

Human

Applications

IHC-p,WB

Modification

Unmodfied/ Total

Source

Monoclonal Mouse

Dilution

IHC-p1:50-200 ,WB 1:1000-2000

Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Storage and Stability

-20°C/1 year

Other Name

Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit]

Molecular Weight (Da)

Gene Name

NFKB1

Protein Name

NF κB P50

Human Gene ID

4790

Human Swiss Prot No.

P19838

Immunogen

Synthesized peptide derived from human NF κB P50

Specificity