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PI3 Kinase P85α Monoclonal Antibody(3B7)
PI3 Kinase P85α Monoclonal Antibody(3B7)

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: N1540
Reactivity:Rat,Mouse
Applications:WB,IHC-p,IF(paraffin section)
Modification:Unmodfied/ Total
Source:Monoclonal Mouse
Storage and Stability:-20°C/1 year

$160
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PI3 Kinase P85α Monoclonal Antibody(3B7)

Western blot analysis of 1)3T3. 2) Rat LiverTissue with PI3 Kinase P85α Mouse mAb diluted at 1:2.000.

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Product Details
Product Name
PI3 Kinase P85α Monoclonal Antibody(3B7)
Description
Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD.This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011],
Catalog No
N1540
Reactivity
Rat,Mouse
Applications
WB,IHC-p,IF(paraffin section)
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
WB 1:1000-2000, IHC 1:100-200
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
PIK3R1; GRB1; Phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alpha
Molecular Weight (Da)
Gene Name
PIK3R1
Protein Name
Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85
Human Gene ID
5295
Human Swiss Prot No.
P27986
Immunogen
Recombinant Protein of PI3 Kinase P85α
Specificity
PI3 Kinase P85α protein detects endogenous levels of PI3 Kinase P85α
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (11)
The PI3K/p-Akt signaling pathway participates in calcitriol ameliorating podocyte injury in DN rats. METABOLISM-CLINICAL AND EXPERIMENTAL Metabolism. 2014 Oct;63:1324 WB Rat Renal tissues

Author: Available in link provided

Date of Publication : Available in link provided

Deficiency in the short‐chain acyl‐CoA dehydrogenase protects mice against diet‐induced obesity and insulin resistance. FASEB JOURNAL Faseb J. 2019 Dec;33(12):13722-13733 WB Mouse liver hepatocytes

Author: Available in link provided

Date of Publication : Available in link provided

Polygonum cuspidatum Extract Exerts Antihyperlipidemic Effects by Regulation of PI3K/AKT/FOXO3 Signaling Pathway. Oxidative Medicine and Cellular Longevity Oxid Med Cell Longev. 2021;2021:3830671 WB Human 1:1000 HepG2 cells

Author: Available in link provided

Date of Publication : Available in link provided

Roles of Nrf2/HO‐1 and HIF‐1α/VEGF in lung tissue injury and repair following cerebral ischemia/reperfusion injury. JOURNAL OF CELLULAR PHYSIOLOGY J Cell Physiol. 2019 Jun;234(6):7695-7707 IHC Rat 1:400 Lung tissue

Author: Available in link provided

Date of Publication : Available in link provided

5‐FU inhibits migration and invasion of CRC cells through PI3K/AKT pathway regulated by MARCH1. CELL BIOLOGY INTERNATIONAL Cell Biol Int. 2021 Feb;45(2):368-381 WB Human Colorectal cancer(CRC ) tissues sw480s,DLD-1s,NCM460s

Author: Available in link provided

Date of Publication : Available in link provided

COX-2/sEH Dual Inhibitor Alleviates Hepatocyte Senescence in NAFLD Mice by Restoring Autophagy through Sirt1/PI3K/AKT/mTOR INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Chen-Yu Zhang WB Mouse

Author: Available in link provided

Date of Publication : Available in link provided

Study of the Mechanism of Astragali Radix in Treating Type 2 Diabetes Mellitus and Its Renal Protection Based on Enzyme Activity, Network Pharmacology, and Experimental Verification MOLECULES Chunnan Li WB Mouse renal tissue

Author: Available in link provided

Date of Publication : Available in link provided

The gut microbiota contributes to the infection of bovine viral diarrhea virus in mice JOURNAL OF VIROLOGY Zecai Zhang WB Mouse peripheral blood lymphocytes (PBL)

Author: Available in link provided

Date of Publication : Available in link provided

NUP85 alleviates lipid metabolism and inflammation by regulating PI3K/AKT signaling pathway in nonalcoholic fatty liver disease International Journal of Biological Sciences Wu Yin-cui WB Mouse AML-12 cell

Author: Available in link provided

Date of Publication : Available in link provided

A novel phthalein component ameliorates neuroinflammation and cognitive dysfunction by suppressing the CXCL12/CXCR4 axis in rats with vascular dementia JOURNAL OF ETHNOPHARMACOLOGY Kai-Ting Ma WB Rat,Mouse 1:2000 brain tissue BV2 cell

Author: Available in link provided

Date of Publication : Available in link provided

Elucidation of the anti-gastric cancer mechanism of Guiqi Baizhu Formula by integrative approach of chemical bioinformatics INTERNATIONAL IMMUNOPHARMACOLOGY Yanru Wang WB Human MKN-45 cell

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

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    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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