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Primary Antibodies
PI 3-kinase p85α Antibody
PI 3-kinase p85α Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C30933
Reactivity:Human,Mouse,Rat
Applications:WB,ELISA
Modification:Unmodified/Total
Source:Polyclonal Rabbit
Storage and Stability:-20°C/1 year

$205
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PI 3-kinase p85α Antibody

Western Blot analysis of various cells using primary antibody diluted at 1:500(4°C overnight). Secondary antibody:Goat Anti-rabbit IgG IRDye 800( diluted at 1:5000, 25°C, 1 hour)

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Product Details
Product Name
PI 3-kinase p85α Antibody
Description
Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]
Catalog No
C30933
Reactivity
Human, Mouse, Rat
Applications
WB, ELISA
Modification
Unmodified/Total
Source
Polyclonal Rabbit
Dilution
WB 1:500-2000, ELISA 1:10000-20000
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
PIK3R1; GRB1; Phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alph
Molecular Weight (Da)
83598/54462
Gene Name
PIK3R1
Protein Name
Phosphatidylinositol 3-kinase regulatory subunit alpha
Human Gene ID
5295
Human Swiss Prot No.
P27986
Immunogen
Synthesized peptide derived from PI 3-kinase p85α . at AA range: 550-630
Specificity
This antibody detects endogenous levels of PI 3-kinase p85α.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (8)
Proteomic Study on the Reproductive Toxicity of Tripterygium Glycosides in Rats

Author: Dai Yanlin, Sun Lihui, Han Shanshan, Xu Shanshan, Wang Long, Ding Ying

Date of Publication : 2022-05-20

Induction of PI3K/Akt-Mediated Apoptosis in Osteoclasts Is a Key Approach for Buxue Tongluo Pills to Treat Osteonecrosis of the Femoral Head.

Author: Wang D, Liu Y, Tang D, Wei S, Sun J, Ruan L, He L, Li R, Ren Q, Tian X, Chen Y

Date of Publication : 2021-11-29

CypB promotes cell proliferation and metastasis in endometrial carcinoma

Author: Liu, Jing, Zuo, Ying, Qu, Gui-Mei, Song, Xiao, Liu, Zhong-Hui, Zhang, Ting-Guo, Zheng, Zhu-Hua, Wang, Hong-Kun

Date of Publication : 2021-06-29

iTRAQ-Based Proteomics Reveals Gu-Ben-Fang-Xiao Decoction Alleviates Airway Remodeling via Reducing Extracellular Matrix Deposition in a Murine Model of Chronic Remission Asthma

Author: Qiongqiong Xing, Yannan You, Xia Zhao, Jianjian Ji, Hua Yan, Yingmei Dong, Lishun Ren, Yuanyuan Ding, Shuting Hou

Date of Publication : 2021-06-14

An Integrated Approach Based on Network Pharmacology Combined with Experimental Verification Reveals AMPK/PI3K/Akt Signaling is an Important Way for the Anti-Type 2 Diabetic Activity of Silkworm Excrement

Author: Huxinyue Duan, Qing Zhang, Jia Liu, Ruolan Li, Wei Peng, Chunjie Wu

Date of Publication : 2021-02-11

5‐FU inhibits migration and invasion of CRC cells through PI3K/AKT pathway regulated by MARCH1

Author: Nuan Wang, Lijuan Yang, Juanjuan Dai, Yan Wu, Ranran Zhang, Xingfang Jia, Chengxia Liu

Date of Publication : 2020-10-29

Scutellarin Prevents Nonalcoholic Fatty Liver Disease (NAFLD) and Hyperlipidemia via PI3K/AKT-Dependent Activation of Nuclear Factor (Erythroid-Derived 2)-Like 2 (Nrf2) in Rats

Author: Hua Fan, Xiande Ma, Peng Lin, Qiang Kang, Zhilong Zhao, Lina Wang, Dan Sun, Jiayi Cheng, Yajun Li

Date of Publication : 2017-11-24

HMGB1 binding to receptor for advanced glycation end products enhances inflammatory responses of human bronchial epithelial cells by activating p38 MAPK and ERK1/2

Author: Yue Liang, Changchun Hou, Jinliang Kong, Hanchun Wen, Xiaowen Zheng, Lihong Wu, Hong Huang, Yiqiang Chen

Date of Publication : 2015-04-11

Primary Antibodies

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    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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