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Primary Antibodies
PI 3-kinase p85α (Phospho-Tyr607) Antibody
PI 3-kinase p85α (Phospho-Tyr607) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A1225
Reactivity:Human,Mouse,Rat,Chicken(testedbyourcustomer）
Applications:IF/ICC,WB,IHC-p,ELISA
Modification:Phospho Specific
Source:Polyclonal Rabbit
Storage and Stability:-20°C/1 year

$205
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PI 3-kinase p85α (Phospho-Tyr607) Antibody

Western Blot analysis of KB cells using Phospho-PI 3-kinase p85α (Y607) Polyclonal Antibody diluted at 1:1000

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Product Details
Product Name
PI 3-kinase p85α (Phospho-Tyr607) Antibody
Description
Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]
Catalog No
A1225
Reactivity
Human, Mouse, Rat, Chicken(testedbyourcustomer）
Applications
IF/ICC, WB, IHC-p, ELISA
Modification
Phospho Specific
Source
Polyclonal Rabbit
Dilution
IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
PIK3R1; GRB1; Phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alph
Molecular Weight (Da)
83598
Gene Name
PIK3R1
Protein Name
Phosphatidylinositol 3-kinase regulatory subunit alpha
Human Gene ID
5295
Human Swiss Prot No.
P27986
Immunogen
The antiserum was produced against synthesized peptide derived from human PI3-kinase p85-alpha around the phosphorylation site of Tyr607. AA range:573-622
Specificity
Phospho-PI 3-kinase p85α (Y607) Polyclonal Antibody detects endogenous levels of PI 3-kinase p85α protein only when phosphorylated at Y607.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (7)
Licoflavone A Suppresses Gastric Cancer Growth and Metastasis by Blocking the VEGFR-2 Signaling Pathway

Author: Hongxia Gong, Xiaojie Jin, Guangxian Leng, Min Zhang, Shiwei Niu, Wangjie Cao, Han Zhang, Yuanding Zeng, Chenghao Li, Yaling Li, Yun Su, Yongqi Liu

Date of Publication : 2022-04-25

Morphine promotes the malignant biological behavior of non-small cell lung cancer cells through the MOR/Src/mTOR pathway

Author: Liu, Xingyun, Yang, Jia, Yang, Chengwei, Huang, Xiang, Han, Mingming, Kang, Fang, Li, Juan

Date of Publication : 2021-11-25

Isorhamnetin Promotes MKN-45 Gastric Cancer Cell Apoptosis by Inhibiting PI3K-Mediated Adaptive Autophagy in a Hypoxic Environment

Author: Chenghao Li, Jiawei Li, Yan Li, Ling Li, Yali Luo, Junjie Li, Yiming Zhang, Yanru Wang, Xiuzhu Liu, Xiaotian Zhou, Hongxia Gong, Xiaojie Jin, Yongqi Liu

Date of Publication : 2021-07-16

5‐FU inhibits migration and invasion of CRC cells through PI3K/AKT pathway regulated by MARCH1

Author: Nuan Wang, Lijuan Yang, Juanjuan Dai, Yan Wu, Ranran Zhang, Xingfang Jia, Chengxia Liu

Date of Publication : 2020-10-29

The Effects of Maternal Atrazine Exposure and Swimming Training on Spatial Learning Memory and Hippocampal Morphology in Offspring Male Rats via PSD95/NR2B Signaling Pathway

Author: Wang, Dandan, Li, Bai, Wu, Yanping, Li, Baixiang

Date of Publication : 2019-06-11

PM2.5 induces autophagy-mediated cell death via NOS2 signaling in human bronchial epithelium cells

Author: Xiao-Ming Zhu, Qin Wang, Wei-Wei Xing, Min-Hui Long, Wen-Liang Fu, Wen-Rong Xia, Chen Jin, Ning Guo, Dong-Qun Xu, Dong-Gang Xu

Date of Publication : 2018-04-05

Luteolin induces apoptosis in vitro through suppressing the MAPK and PI3K signaling pathways in gastric cancer

Author: Xueying Lu, Yanhong Li, Xiaobo Li, Haji Akber Aisa

Date of Publication : 2017-08-01

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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