HIF-1 β/ARNT Monoclonal Antibody(4C5)

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: N1574

Reactivity:Mouse

Applications:WB,IHC-p,IF(paraffin section)

Modification:Unmodfied/ Total

Source:Monoclonal Mouse

Storage and Stability:-20°C/1 year

Size:

Price/Quantity $160

Quantity:

Datasheet

SDS

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HIF-1 β/ARNT Monoclonal Antibody(4C5)

Western blot analysis of Mouse Brain Tissue with HIF-1 β/ARNT Mouse mAb diluted at 1:2.000.

Delivery

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

Telephone

408-747-0185

Fax

408-747-0145

order@assaybiotech.com

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Product Details

Product Name

HIF-1 β/ARNT Monoclonal Antibody(4C5)

Description

aryl hydrocarbon receptor nuclear translocator(ARNT) Homo sapiens. This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013],

Catalog No

N1574

Reactivity

Mouse

Applications

WB,IHC-p,IF(paraffin section)

Modification

Unmodfied/ Total

Source

Monoclonal Mouse

Dilution

WB 1:1000-2000, IHC 1:100-200

Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Storage and Stability

-20°C/1 year

Other Name

ARNT; BHLHE2; Aryl hydrocarbon receptor nuclear translocator; ARNT protein; Class E basic helix-loop-helix protein 2; bHLHe2; Dioxin receptor, nuclear translocator; Hypoxia-inducible factor 1-beta; HIF-1-beta; HIF1-beta

Molecular Weight (Da)

Gene Name

ARNT

Protein Name

Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Class E basic helix-loop-helix protein 2) (bHLHe2) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1-beta) (HIF-1-beta) (HIF1-beta)

Human Gene ID

405

Human Swiss Prot No.

P27540

Immunogen

Recombinant Protein of HIF-1 β

Specificity

HIF-1 β/ARNT protein detects endogenous levels of HIF-1 β/ARNT

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.