ribosomal protein S6 kinase B1(RPS6KB1)Homo sapiens. This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013],
Catalog No
N1586
Reactivity
Human,Rat,Mouse
Applications
IHC-p,IF(paraffin section)
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
IHC 1:100-200
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
RPS6KB1
Molecular Weight (Da)
Gene Name
RPS6KB1
Protein Name
RPS6KB1
Human Gene ID
6198
Human Swiss Prot No.
P23443
Immunogen
Recombinant Protein of P70 S6 Kinase of RPS6KB1
Specificity
P70 S6 Kinase protein detects endogenous levels of RPS6KB1
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
