glycogen synthase kinase 3 beta(GSK3B) Homo sapiens. The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009],
Catalog No
N1615
Reactivity
Human,Rat,Mouse
Applications
WB,IHC-p,IF(paraffin section)
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
WB 1:1000-2000, IHC 1:100-200
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
GSK3B
Molecular Weight (Da)
Gene Name
GSK3B
Protein Name
GSK3B
Human Gene ID
2932
Human Swiss Prot No.
P49841
Immunogen
Synthetic Peptide of GSK3β at AA range of 1-80
Specificity
GSK3β protein detects endogenous levels of GSK3B
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
