histone cluster 1 H3 family member a(HIST1H3A) Homo sapiens. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015],
Catalog No
N1625
Reactivity
Human,Rat,Mouse
Applications
IHC-p,IF(paraffin section)
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
IHC 1:100-200
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
HIST1H3A;H3k9AC
Molecular Weight (Da)
Gene Name
HIST1H3A
Protein Name
HIST1H3A
Human Gene ID
8290
Human Swiss Prot No.
P68431
Immunogen
Synthetic Peptide of Acetyl-Histone H3 (K9)
Specificity
Acetyl-Histone H3 (K9) Monoclonal Antibody(2E7) detects endogenous levels of HIST1H3A
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
