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Mast cell tryptase (PT2024) mouse mAb
Mast cell tryptase (PT2024) mouse mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: N1852
Reactivity:Human,Mouse
Applications:IHC-p,IF(paraffin section)
Modification:Unmodfied/ Total
Source:Monoclonal Mouse/IgG1,Kappa
Storage and Stability:-20°C/1 year

$190
Product Details
Product Name
Mast cell tryptase (PT2024) mouse mAb
Description
Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate gene
Catalog No
N1852
Reactivity
Human, Mouse
Applications
IHC-p,IF(paraffin section)
Modification
Unmodfied/ Total
Source
Monoclonal Mouse/IgG1, Kappa
Dilution
WB 500-2000 IHC-p 1:100-500
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Concentration
Storage and Stability
-20°C/1 year
Other Name
Molecular Weight (Da)
Gene Name
TPSAB1 TPS1 TPS2 TPSB1
Protein Name
Tryptase alpha/beta-1 (Tryptase-1) (EC 3.4.21.59) (Tryptase I) (Tryptase alpha-1)
Human Gene ID
7177
Human Swiss Prot No.
Q15661
Immunogen
Synthesized peptide derived from human Mast cell tryptase
Specificity
This antibody detects endogenous levels of human Mast cell tryptase. Heat-induced epitope retrieval (HIER) Citrate buffer of pH6.0 was highly recommended as antigen repair method in paraffin section
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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