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> Products > Primary Antibodies > SphK2 Antibody

SphK2 Antibody

Overview Description
Datasheet SDS
   Kinases and Phosphatases   
Catalog No : B8423
  • Reactivity
    Human,Mouse,Rat
  • Applications
    WB,IHC-p,IF(paraffin section),ELISA
  • Modification
    Unmodified/Total
  • Source
    Polyclonal Rabbit
  • Storage and Stability
    -20°C/1 year
  • Size
    50 μl
  • Price/Quantity
    $205
  • Quantity
Add to Cart
Details
  • Product Name
    SphK2 Antibody
  • Description
    This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]
  • Catalog No
    B8423
  • Reactivity
    Human, Mouse, Rat
  • Applications
    WB, IHC-p, IF(paraffin section), ELISA
  • Modification
    Unmodified/Total
  • Source
    Polyclonal Rabbit
  • Dilution
    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
  • Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration
    1 mg/ml
  • Storage and Stability
    -20°C/1 year
  • Other Name
    SPHK2; Sphingosine kinase 2; SK 2; SPK 2
  • Molecular Weight (Da)
    69217
  • Gene Name
    SPHK2
  • Protein Name
    Sphingosine kinase 2
  • Human Gene ID
    56848
  • Human Swiss Prot No.
    Q9NRA0
  • Immunogen
    The antiserum was produced against synthesized peptide derived from human SPHK2. AA range:580-629
  • Specificity
    SphK2 Polyclonal Antibody detects endogenous levels of SphK2 protein.
  • Formulation
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Application Data
Western blot analysis of lysates from 293 cells, using SPHK2 Antibody. The lane on the right is blocked with the synthesized peptide.
Application Data
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using SPHK2 Antibody. The picture on the right is blocked with the synthesized peptide.
Application Data
Western Blot analysis of AD293 using SphK2 Polyclonal Antibody diluted at 1:500
Application Data
Western Blot analysis of 22RV1 cells using SphK2 Polyclonal Antibody diluted at 1:500
Publications

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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