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Primary Antibodies
SphK2 Antibody
SphK2 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: B8423
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,IF,ELISA
Modification:Unmodified/Total
Source:Polyclonal,Rabbit,IgG
Storage and Stability:Store at -20°C/1 year

$205
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SphK2 Antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using SPHK2 Antibody. The picture on the right is blocked with the synthesized peptide.

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Product Details
Product Name
SphK2 Antibody
Description
This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011],
Catalog No
B8423
Reactivity
Human, Mouse, Rat
Source
Polyclonal, Rabbit,IgG
Modification
Unmodified/Total
Applications
WB, IHC, IF, ELISA
Dilution
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
SPHK2; Sphingosine kinase 2; SK 2; SPK 2
Molecular Weight (Da or kDa)
Gene Name
SPHK2
Protein Name
Sphingosine kinase 2
Human Gene ID
56848
Human Swiss Prot No.
Q9NRA0
Immunogen
The antiserum was produced against synthesized peptide derived from human SPHK2. AA range:580-629
Specificity
SphK2 Polyclonal Antibody detects endogenous levels of SphK2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (1)
Reticulon 3 regulates sphingosine-1-phosphate synthesis in endothelial cells to control blood pressure MedComm Jie-Yuan Jin WB Human 1:1000 human umbilical vein endothelial cells (HUVECs)

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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